Cas No.: | 2082762-29-4 |
Chemical Name: | (E)-3-((3-bromophenyl)(2-carbamothioylhydrazono)methyl)phenyl dihydrogen phosphate, disodium salt |
Synonyms: | KGP420 |
Formula: | C14H13BrN3Na2O4PS |
M.Wt: | 476.192 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | KGP-420 is the water-soluble phosphate prodrug of KGP-94 in vivo studies, KGP-94 is a potent, selective cathepsin L inhibitor with IC50 of 189 nM; readily converts to KGP-94, and shows cytotoxicity against HUVECs with GI50 of 20.2 uM. |