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VPC-80051(VPC80051)

  Cat. No.:  DC23744   Featured
Chemical Structure
877969-69-2
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More than 5000 active chemicals with high quality for research!
Field of application
VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 877969-69-2
Chemical Name: (S)-N-(1-(3,4-Difluorophenyl)ethyl)-1H-indazole-3-carboxamide
Synonyms: (S)-N-(1-(3,4-Difluorophenyl)ethyl)-1H-indazole-3-carboxamide
SMILES: FC1=C(C([H])=C([H])C(=C1[H])[C@]([H])(C([H])([H])[H])N([H])C(C1C2=C([H])C([H])=C([H])C([H])=C2N([H])N=1)=O)F
Formula: C16H13F2N3O
M.Wt: 301.2907
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: VPC-80051 (VPC80051) is the first small molecule inhibitor of hnRNP A1 splicing activity, targets RNA-binding domain (RBD) of hnRNP A1; interacts directly with hnRNP A1 RBD and reduces AR-V7 messenger levels in 22Rv1 CRPC cell line, reduces AR-V7 mRNA levels.
References: References 1. Carabet LA, et al. Molecules. 2019 Feb 20;24(4). pii: E763. View Related Products by Target Spliceosome
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
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