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AK778

  Cat. No.:  DC23789   Featured
Chemical Structure
328906-67-8
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More than 5000 active chemicals with high quality for research!
Field of application
AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix. .
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 328906-67-8
Chemical Name: 2-[[5-(1H-Benzimidazol-2-yl)-2-methylphenyl]iminomethyl]-4-benzyl-6-nitrophenol
Synonyms: Oprea1_106567;AK778;2-(((5-(1H-Benzo[d]imidazol-2-yl)-2-methylphenyl)imino)methyl)-4-benzyl-6-nitrophenol;2-[[5-(1H-Benzimidazol-2-yl)-2-methylphenyl]iminomethyl]-4-benzyl-6-nitrophenol
SMILES: OC1C(=CC(=CC=1/C=N/C1=C(C)C=CC(=C1)C1=NC2C=CC=CC=2N1)CC1C=CC=CC=1)[N+](=O)[O-]
Formula: C28H22N4O3
M.Wt: 462.499286174774
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.
References: References 1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085. View Related Products by Target Heat Shock Protein (HSP)
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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