AK778 (Col001)| CAS 328906-67-8|Hsp47 inhibitor

Cas No.:	328906-67-8
Chemical Name:	2-[[5-(1H-Benzimidazol-2-yl)-2-methylphenyl]iminomethyl]-4-benzyl-6-nitrophenol
Synonyms:	Oprea1_106567;AK778;2-(((5-(1H-Benzo[d]imidazol-2-yl)-2-methylphenyl)imino)methyl)-4-benzyl-6-nitrophenol;2-[[5-(1H-Benzimidazol-2-yl)-2-methylphenyl]iminomethyl]-4-benzyl-6-nitrophenol
SMILES:	OC1C(=CC(=CC=1/C=N/C1=C(C)C=CC(=C1)C1=NC2C=CC=CC=2N1)CC1C=CC=CC=1)[N+](=O)[O-]
Formula:	C₂₈H₂₂N₄O₃
M.Wt:	462.499286174774
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	AK778 (Col001) is a small-molecule compound that inhibits the interaction of Hsp47 with collagen, competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.
References:	References 1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085. View Related Products by Target Heat Shock Protein (HSP)

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