Cas No.: | 1269055-85-7 |
Chemical Name: | Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro- |
Synonyms: | FAB-001 |
SMILES: | CCC1C(F)=CC(OC2C(F)=CC(C(=O)N)=CC=2)=C(O)C=1 |
Formula: | C15H13F2NO3 |
M.Wt: | 293.2654 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli; shows activity against S. aureus strains, including MSSA, MRSA, linezolid-resistant, and multidrug-resistant strains with MIC90s of 0.03-0.12 ug/ml; also has active against coagulase-negative staphylococci with MIC90s of 0.12-4 ug/ml; active in vivo (19.3-49.6 mg/kg/day).Bacterial InfectionPreclinical |