Cas No.: | 1049741-55-0 |
Chemical Name: | Cardiogenol C HCl |
SMILES: | [H]Cl.COC1C=CC(NC2N=C(NCCO)C=CN=2)=CC=1 |
Formula: | C13H17ClN4O2 |
M.Wt: | 296.755 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Cardiogenol C is a small cell-permeable molecule that selectively and efficiently induce mouse embryonic stem cells (ESCs) to differentiate into cardiomyocytes with EC50 of 0.1 uM; induces cardiac differentiation in P19 and in P19Cl6 cells, also induces hair bulge progenitor cells (HBPCs) to express transcription factors GATA4, Nkx2.5 and Tbx5, Cardiogenol C might exert its effect by activating the Wnt signaling pathway through the suppression of Kremen1. |