Cas No.: | 1948-33-0 |
Chemical Name: | 1,4-Benzenediol, 2-(1,1-dimethylethyl)- |
Synonyms: | tert-Butylhydroquinone |
SMILES: | C(C1C=C(O)C=CC=1O)(C)(C)C |
Formula: | C10H14O2 |
M.Wt: | 166.217 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A phenolic antioxidant and a selective inducer and activator of Nrf2 that ameliorates doxorubicin-induced cardiotoxicity in vivo; ameliorates the doxorubicin-induced oxidative stress and apoptosis, increases the nuclear accumulation of Nrf2 and the Nrf2-regulated gene expression, including HO-1 and NQO-1 expression; also ameliorates early brain injury after experimental subarachnoid emorrhage in mice by enhancing Nrf2-independent autophagy. |