FDL-169|CAS 1628416-28-3|CFTR inhibitor

Cas No.:	1628416-28-3
Chemical Name:	CFTR corrector 2
Synonyms:	CFTR corrector 2;FDL169;2-(7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo[d]oxazol-6-yl)acetamide;2-[7-ethoxy-4-(3-fluorophenyl)-1-oxo-1,2-dihydrophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide;XRPSUWYWZUQALB-UHFFFAOYSA-N;BDBM160525;BCP30546;ZB1606;s8795;SB18874;US9682969, 22;US9682969, 17;49PN4S4FDH;AKOS037515658;MS-29036;2-[7-ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2-yl]-N-methyl-N-(2-methyl-1,3-benzoxazol-6-yl)acetamide;HY-125381;7-Ethoxy-4-(3-fluorophenyl)-N-methyl-N-(2-methyl-6-benzoxazolyl)-1-oxo-2(1H)-phthalazineacetamide;FDL-169;FDL 169;2-(7-Ethoxy-4-(3-fluorophenyl)-1-oxophthalazin-2(1H)-yl)-N-methyl-N-(2-methylbenzo(d)oxazol-6-yl)acetamide;SCHEMBL16048480;CS-0091038;G16731;CHEMBL5095180;1628416-28-3;2(1H)-Phthalazineacetamide, 7-ethoxy-4-(3-fluorophenyl)-N-methyl-N-(2-methyl-6-benzoxazolyl)-1-oxo-;DA-53138;UNII-49PN4S4FDH;EX-A3163;FDL-169
SMILES:	FC1=CC=CC(=C1)C1C2C=CC(=CC=2C(N(CC(N(C)C2=CC=C3C(=C2)OC(C)=N3)=O)N=1)=O)OCC
Formula:	C₂₇H₂₃FN₄O₄
M.Wt:	486.494329690933
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

FDL-169 is a novel and potent CFTR (Cystic fibrosis transmembrane conductance regulator) corrector being developed by Flatley Discovery Lab for treating cystic fibrosis (CF) patients who carry the F508del mutation, the most common mutation in this disease. Correctors are drugs designed to fix and restore the function of the defective CFTR protein. The corrected CFTR then moves to the cell surface, where it functions as a chloride channel and helps maintain the right balance of fluid in the airways.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

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