Thioquinapiperifil dihydrochloride|CAS 204077-66-7|DC Chemicals

Cas No.:	204077-66-7
Chemical Name:	Thioquinapiperifil Dihydrochloride
Synonyms:	Thioquinapiperifil Dihydrochloride;KF-31327;Thioquinapiperifil D;3-ethyl-8-[[2-[4-(hydroxymethyl)piperidin-1-yl]phenyl]methylamino]-1H-imidazo[4,5-g]quinazoline-2-thione;dihydrochloride;3-Ethyl-8-[2-[4-(hydroxymethyl)piperidin-1-yl]benzylamino]-2,3-dihydro-1H-imidazo[4,5-g]quinazoline-2-thione dihydrochloride;204077-66-7;SCHEMBL1961932;UNII-QJ87H5L241;CS-0159094;HY-119611A;kf31327;Thioquinapiperifil dihydrochloride;3-Ethyl-8-(2-(4-hydroxymethylpiperidino)benzylamino)-2,3-dihydro-1H-imidazo(4,5-g)quinazoline-2-thione dihydrochloride;YWGNFHIWAHNADT-UHFFFAOYSA-N;Q27287290;E77676;KF 31327;2H-Imidazo(4,5-g)quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-(((2-(4-(hydroxymethyl)-1-piperidinyl)phenyl)methyl)amino)-, dihydrochloride;DB-218054;QJ87H5L241;AS-82728;THIOQUINAPIPERIFIL (DIHYDROCHLORIDE);2H-Imidazo(4,5-g)quinazoline-2-thione, 3-ethyl-1,3-dihydro-8-(((2-(4-(hydroxymethyl)-1-piperidinyl)phenyl)methyl)amino)-, hydrochloride (1:2)
SMILES:	CCN1C2=C(C=C3C(=C2)N=CN=C3NCC4=CC=CC=C4N5CCC(CC5)CO)NC1=S.Cl.Cl
Formula:	C₂₄H₂₈N₆Os^.₂[HCl]
M.Wt:	521.5056
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC81677	TRPM5 agonist-1	TRPM5 agonist-1 is an orally active TRPM5 agonist with a pEC50 of 8.1. TRPM5 agonist-1 shows excellent selectivity (> 100-fold) versus related cation channels (TRPM8, TRPV1, TRPV4, TRPA1, TRPM4). TRPM5 agonist-1 exhibits locally acting stimulatory effect on gastrointestinal transit in mice. TRPM5 agonist-1 can be used for research on promoting gastric motility.
DC79747	OncoACP3	OncoACP3 (Compound s43) is a high affinity ligand for prostatic acid phosphatase (ACP3). OncoACP3, radiolabelled with Lu-177, selectively accumulates in enzyme-expressing tumors and shows a potent anti-tumor activity with excellent tumor-selective payload deposition in HT1080.hACP3 and PC3.hACP3 tumor-bearing mice model. OncoACP3 can be used for prostate cancer research.
DC79263	ACP3 ligand 1	ACP3 ligand 1 (compound I11a) is a ligand against Acid Phosphatase 3 (ACP3, ACPP). ACP3 ligand 1 interacts with ACP3 expressed on the surface of tumor cells for in vivo pharmaco-delivery applications.
DC78771	(R)-SW033291	(R)-SW033291 is the R-type enantiomer of SW033291. (R)-SW033291 is a potent and high-affinity inhibitor of 15-PGDH. (R)-SW033291 increases prostaglandin PGE2 levels in bone marrow and other tissues. (R)-SW033291 also promotes tissue regeneration.
DC78715	MF-DH-300	MF-DH-300 is a 15-PGDH inhibitor with an IC50 of 1.6 nM. MF-DH-300 blocks binding of 15-PGDH to PGE2 and increases stem cell proliferation and muscle force, as well as improves mitochondrial function. MF-DH-300 increases survival motor neuron (SMN) protein expression. MF-DH-300 can be used for muscle disorders like spinal muscular atrophy (SMA) research.
DC78548	ISM5939	ISM5939 is an orally active and selective ENPP1 inhibitor with an IC50 of 0.63 nM for 2,3-cGAMP degradation and 9.28 nM for ATP hydrolysis. ISM5939 has antitumor activity.
DC76915	3-Epideoxycholic acid	3-Epideoxycholic acid is the microbial metabolite of Deoxycholic acid. 3-Epideoxycholic acid targets FXR of dendritic cells, reduces their immunostimulatory properties, promotes the generation of Treg cells, and exhibits anti-inflammatory activity. 3-Epideoxycholic acid promotes the growth of bacteria Bacteroides.
DC76881	GK420	GK420 (AVX420) is a potent inhibitor of cytosolic phospholipase A2α (cPLA2α), with the XI(50) of 0.0016. GK420 inhibits arachidonic acid release with the EC50 of 0.09 μM. GK420 plays an important role in cancer research.
DC73797	TPT-004	TPT-004 is a highly potent, selective tryptophan hydroxylase (TPH) with IC50 of 77 nM and 16 nM for TPH1 and TPH2, respectively.
DC73792	NSC74429	NSC74429 is a CNS-active, small molecule PHLPP inhibitor with IC50 of <5 uM, shows neuroprotective activity in primary rat cortical neurons in STS assay.