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MMH2-NR

  Cat. No.:  DC67341   Featured
Chemical Structure
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Field of application
MMH2-NR serves as an essential negative control compound for MMH2, a novel DCAF16-dependent BRD4 degrader. While MMH2 mediates targeted protein degradation by recruiting the CUL4-DCAF16 E3 ligase complex to bromodomain-containing protein 4 (BRD4), MMH2-NR is structurally analogous but lacks degradation activity, making it critical for mechanistic validation.
Cas No.:
Chemical Name: MMH2-NR
SMILES: CC1=C(C)SC2=C1C(C3=CC=C(NS(CC)(=O)=O)C=C3)=N[C@@H](CC(OC(C)(C)C)=O)C4=NN=C(C)N42
Formula: C25H31N5O4S2
M.Wt: 529.67
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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