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Lenalidomide-13C5,15N

Cat. No.: DC67367 Featured

Chemical Structure

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Field of application

Lenalidomide-13C5,15N is an isotopically labeled analog of lenalidomide (HY-A0003; CC-5013), a thalidomide-derived molecular glue compound. This orally bioavailable immunomodulator functions through selective cereblon (CRBN) E3 ubiquitin ligase engagement, mediating targeted ubiquitination and proteasomal degradation of lymphoid transcription factors IKZF1 and IKZF3 via the CRBN-CRL4 complex. The compound demonstrates dual therapeutic activity by both suppressing proliferation of mature B-cell malignancies (including multiple myeloma) and enhancing T-cell immunostimulation through IL-2 induction.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:
Chemical Name:	Lenalidomide-13C5,15N
Synonyms:	CC-5013-13C5,15N
SMILES:	O=C1C2=CC=CC(N)=C2C[15N]1[13CH]([13C](N3)=O)[13CH2][13CH2][13C]3=O
Formula:	C₈₁₃C₅H₁₃N₂₁₅NO₃
M.Wt:	265.22
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68076	BG-BRD4-P07
DC68075	BRU-SHP2-P06
DC68074	LLY-ESR1-P05
DC68073	AST-AR-P04
DC68072	NOV-EP001
DC68071	JHU-MDM2-P03
DC68070	CAS-FAK-P02
DC68069	MDA-S24-P01
DC68068	TB-008
DC68067	ARV-863

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.