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AR Degrader-2

  Cat. No.:  DC67369   Featured
Chemical Structure
3023359-76-1
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More than 5000 active chemicals with high quality for research!
Field of application
AR Degrader-2 (Compound 2) is a molecular glue compound that induces targeted degradation of the androgen receptor (AR), demonstrating potent activity with a DC50 ranging from 0.3 to 0.5 μM in VCaP prostate cancer cells.
Cas No.: 3023359-76-1
Chemical Name: AR Degrader-2
SMILES: CC(C)([C@H](C1(C)C)NC(C2=CC=C(N3CCC(CC3)C(N4CCN(CC4)C(/C(C#N)=C/C(C)(C)C)=O)=O)C=C2)=O)[C@H]1OC5=CC(Cl)=C(C=C5)C#N
Formula: C40H49ClN6O4
M.Wt: 713.31
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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