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PROTAC GSPT1 degrader-2

  Cat. No.:  DC67392   Featured
Chemical Structure
3024909-61-0
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More than 5000 active chemicals with high quality for research!
Field of application
PROTAC GSPT1 degrader-2 (compound A) is a highly efficient molecular glue that achieves near-complete GSPT1 degradation (>95%). This compound demonstrates potent anti-proliferative activity in HL-60 leukemia cells, with an IC50 value of 10 nM, highlighting its therapeutic potential.
Cas No.: 3024909-61-0
Chemical Name: PROTAC GSPT1 degrader-2
SMILES: O=C1NC(C(CC1)N2C(C3=CC=C(N4CCC(CC4)CN5C(N(CCC5)C6=CC(C7=C(Cl)C8=C(NC=C8CC)N=C7)=CC=C6)=O)C=C3C2=O)=O)=O
Formula: C38H38ClN7O5
M.Wt: 708.21
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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