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IKZF1-degrader-1

  Cat. No.:  DC67407   Featured
Chemical Structure
2915586-02-4
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More than 5000 active chemicals with high quality for research!
Field of application
IKZF1-degrader-1 (Compound 9-B) is a highly potent molecular glue that achieves sub-nanomolar degradation of IKZF1 (DC50 = 0.134 nM), demonstrating significant therapeutic potential for targeting IKZF1-dependent malignancies.
Cas No.: 2915586-02-4
Chemical Name: IKZF1-degrader-1
SMILES: O=C1N([C@@H]2C(NC(CC2)=O)=O)C3=CC=C(C4=CC(F)=CC1=C43)CC5=CC=C(C=C5)CN6CCN(C7=C(C=C(C=C7)C#N)F)CC6
Formula: C35H29F2N5O3
M.Wt: 605.63
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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