Dapivirine|cas 244767-67-7|DC Chemicals

Cas No.:	244767-67-7
Chemical Name:	Dapivirine
Synonyms:	Benzonitrile,4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-;Dapivirine (TMC120);4-[[4-(2,4,6-trimethylanilino)pyrimidin-2-yl]amino]benzonitrile;4-[[4-[(2,4,6-Trimethylphenyl)amino]-2-pyrimidinyl]amino]benzonitrile;Dapivirine;TMC-120;4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzenecarbonitrile;dapivirinum;R 147681;TMC120;UNII-TCN4MG2VXS;TMC 120;TMC 120R147681;R147681;Dapivirine(TMC120);TCN4MG2VXS;Benzonitrile, 4-[[4-[(2,4,6-trimethylphenyl)amino]-2-pyrimidinyl]amino]-;4-[4-(2,4,6-TRIMETHYL-PHENYLAMINO)-PYRIMIDIN-2-YLAMINO]-BENZONITRILE;AK326148;4-((4-(mesitylamino)pyrimidin-2-yl)amino)benzonitrile;4-({4-[(2,4,6-trimethylphenyl)amino]pyrimidin-2-yl}amino)benzonitr
SMILES:	N([H])(C1C([H])=C([H])N=C(N([H])C2C([H])=C([H])C(C#N)=C([H])C=2[H])N=1)C1C(C([H])([H])[H])=C([H])C(C([H])([H])[H])=C([H])C=1C([H])([H])[H]
Formula:	C₂₀H₁₉N₅
M.Wt:	329.3984
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

apivirine(TMC 120, TMC 120 R147681) is a NNRTI for HIV reverse transcriptase with IC50 of 24 nM, inhibits a broad panel of HIV-1 isolates from different classes, inclucing a wide range of NNRTI-resistant isolates.

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