Deferitrin|cas 239101-33-8|DC Chemicals

Cas No.:	239101-33-8
Chemical Name:	Deferitrin
Synonyms:	Deferitrin;(2Z,4S)-2-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)-4-methyl-1,3-thiazolidine-4-carboxylic acid;4'-Hydroxydesazadesferrithiocin;GT 56-252;UNII-T69Y9LDN44;4,5-Dihydro-2-(2,4-dihydroxyphenyl)-4-methylthiazol-4-(S)-carboxylic acid
SMILES:	O=C([C@]1(C)N=C(C2=CC=C(O)C=C2O)SC1)O
Formula:	C₁₁H₁₁NO₄S
M.Wt:	253.274
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	Deferitrin (GT-56-252), a desferrithiocin (DFT) analogue, is an orally active trident iron chelator. Deferitrin is used for chronic iron overload due to transfusional therapy. Deferitrin has the potential for beta-thalassemia major[1][2].
In Vitro:	The iron-clearing efficiency (ICE) of Deferitrin (GT-56-252) in a non-iron-overloaded rodent model after oral (po) administration at 300 µmol/kg is shown to be 1.1%[1].

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