Goitrine|cas 1072-93-1|DC Chemicals

Cas No.:	1072-93-1
Chemical Name:	Epigoitrin
Synonyms:	Epigoitrin;D-Goitrin;(R)-5-Ethenyl-2-oxazolidinethione;Goitrine;5-vinyl-2-oxazolidinethione;5-VINYL-2-THIOOXAZOLIDONE;5-vinyloxazolidine-2-thione;Goitrine Epigoitrin;R-GOITRIN;BA-51-090278;Goitrine Epigoitrin;(-)5-VINYL-2-OXAZOLIDINETHIONE;(R)-5-Vinyl-2-oxazolidinethione;Table in the spring;(R,S)-goitrin;Epigoitrin/(R,S)-goitrin;(R)-Goitrin;C5H7NOS;R-5-Vinyl-2-oxazolidinethione;2-Oxazolidinethione, 5-vinyl-, (R)-;Goitrin;(r)-5-vinyloxazolidine-2-thione;(5R)-5-vinyloxazolidine-2-thione;2N815D740R;2-Oxazolidinethione, 5-ethenyl-, (5R)-;Epigotrin;(5R)-5-ethenyl-1,3-oxazolidine-2-thione;goitrin, (R)-isomer;2-Oxazolidinethione, 5-ethenyl-, (R)-;2-O;Ethyl-p-methoxycinnamate;2-Oxazolidinethione, 5-ethenyl-, (R)- (9CI);s9078;FCH844233
SMILES:	S=C1O[C@H](C=C)CN1
Formula:	C₅H₇NOs
M.Wt:	129.1802
Purity:	>98%, Standard References Grade
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:	Epigoitrin is a natural alkaloid from Isatis indigotica, with antiviral activities. Epigoitrin reduces susceptibility to influenza virus via mitochondrial antiviral signaling[1][2].
References:	[1]. Luo Z, et al. Epigoitrin, an Alkaloid From Isatis indigotica, Reduces H1N1 Infection in Stress-Induced Susceptible Model in vivo and in vitro. Front Pharmacol. 2019 Feb 7;10:78. [2]. Xiao P, et al. Antiviral activities against influenza virus (FM1) of bioactive fractions and representative compounds extracted from Banlangen (Radix Isatidis). J Tradit Chin Med. 2016 Jun;36(3):369-76.

Cat. No.	Product name	Field of application
DC82301	IC-8	IC8 is an ionizable cationic lipid. It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs). Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and Omicron variants in mice.1 Administration of mRNA encoding B7-H3 X CD3 bispecific T cell engaging (BiTE) antibodies in IC8-containing LNPs reduces tumor growth in MV4-11 and A375 mouse xenograft models.
DC75721	CL2A-SN38 (Govitecan)	CL2A-SN38 is a SN38 derivative with a peptide-linker which can easily react with antibody to form an antibody-drug conjugate (ADC). CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. .
DC46471	RP101988	RP101988, the major active metabolite of Ozanimod, is a selective, potent S1PR1 (sphingosine-1-phosphate receptor 1) agonist, with EC50s of 0.19 nM and 32.8 nM for S1PR1 and S1PR5, respectivlely.
DC37901	PD-173212	PD-173212 is a small molecule N-type calcium channel blocker.
DC37333	N,N-Diethyl-p-toluamide	N,N-Diethyl-p-toluamide is a mosquito repellent.
DC37321	AI3-15902	AI3-15902 is a biochemical.
DC37283	Methyl phenylcarbamate	Methyl phenylcarbamate is a biochemical.
DC37252	Ampyrone	Ampyrone is a metabolite of AMINOPYRINE with analgesic and anti-inflammatory properties. It is used as a reagent for biochemical reactions producing peroxides or phenols. Ampyrone stimulates LIVER MICROSOMES and is also used to measure extracellular water.
DC37245	Piperonyl butoxide	Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is a waxy white solid. It is a synergist. That is, despite having no pesticidal activity of its own, it enhances the potency of certain pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone.[1] It is a semisynthetic derivative of safrole.
DC34632	MDL800	MDL-800 is a first-in-class cellularly active SIRT6 allosteric activator.

Epigoitrin