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Hydroxy desmethyl Bosentan

  Cat. No.:  DC28843  
Chemical Structure
253688-62-9
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More than 5000 active chemicals with high quality for research!
Field of application
Hydroxy desmethyl Bosentan (Ro 64-105) is a Bosentan metabolism produced by the cytochrome P450 enzymes CYP2C9 and CYP3A4 in the liver. Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Bosentan can be used in treatment of pulmonary arterial hypertension.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 253688-62-9
Formula: C26H27N5O7S
M.Wt: 553.59
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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