Cas No.: | 74356-00-6 |
Chemical Name: | cefotetan sodium |
Synonyms: | cefotetan sodium;Cefotetan Disodium;Disodium (7R)-7-[[4-(carbamoyl-carboxylato-methylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;Apatef;Cefotan;Cefotetan disodium salt;Ceftenon;Cepan;Darvilen;disodium,(6R,7S)-7-[[4-(2-amino-1-carboxylato-2-oxoethylidene)-1,3-dithietane-2-carbonyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;Yamatetan |
SMILES: | COC1(C2SCC(CSC3N(C)N=NN=3)=C(C(O)=O)N2C1=O)/N=C(\[O-])/C1S/C(=C(/C([O-])=N)\C(O)=O)/S1.[Na+].[Na+] |
Formula: | C17H15N7Na2O8S4 |
M.Wt: | 619.59 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Cefotetan Sodium, also known as ICI-156834 and YM-09330, is a second-generation cephalosporin, cephamycin antibiotic that is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative bacteria. Cefotetan binds to penicillin-binding proteins and disrupts the cell wall synthesis. |
References: | [1]. Shi S, et al. Pharmacokinetics and tolerability of intravenous cefotetan disodium for injection in healthy Chinese volunteers: A randomized, open-label, single- and multiple-dose study. |