Cas No.: | 2060530-16-5 |
Chemical Name: | N-(1-(2-(2,4-dichlorophenoxy)acetyl)piperidin-4-yl)-4-mercaptobutanamide |
Synonyms: | KRAS Inhibitor |
SMILES: | C1=CC(Cl)=CC(Cl)=C1OCC(=O)N1CCC(NC(=O)CCCS)CC1 |
Formula: | C17H22Cl2N2O3S |
M.Wt: | 405.34 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | K-Ras(G12C) inhibitor 6 belongs to a series of small molecules, which irreversibly bind to a common oncogenic mutant K-Ras(G12C) and blocks K-Ras(G12C) interactions. Some of them decrease viability and increase apoptosis of G12C-containing cancer cell lines. For the detailed information of K-Ras(G12C) inhibitor 6, the solubility of K-Ras(G12C) inhibitor 6 in water, the solubility of K-Ras(G12C) inhibitor 6 in DMSO, the solubility of K-Ras(G12C) inhibitor 6 in PBS buffer, the animal experiment (test) of K-Ras(G12C) inhibitor 6, the cell expriment (test) of K-Ras(G12C) inhibitor 6, the in vivo, in vitro and clinical trial test of K-Ras(G12C) inhibitor 6, the EC50, IC50,and Affinity of K-Ras(G12C) inhibitor 6, Please contact DC Chemicals. |