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| Cas No.: | 639052-78-1 |
| Chemical Name: | N-(5-Chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide |
| Synonyms: | LH-846;Lh 846;N-(5-chloro-6-methyl-1,3-benzothiazol-2-yl)-2-phenylacetamide;N-(5-Chloro-6-methyl-2-benzothiazolyl)-benzeneacetamide;LH846;Benzeneacetamide, N-(5-chloro-6-methyl-2-benzothiazolyl)-;N-(5-chloro-6-methylbenzo[d]thiazol-2-yl)-2-phenylacetamide;N-(5-Chloro-6-methyl-benzothiazol-2-yl)-2-phenyl-acetamide;Oprea1_693221;N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneacetamide;AOB3510;BCP09669;STK241276;3782AH;BC600442;AK20 |
| SMILES: | ClC1=C([H])C2=C(C([H])=C1C([H])([H])[H])SC(=N2)N([H])C(C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])=O |
| Formula: | C16H13ClN2Os |
| M.Wt: | 316.8052 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | LH846 is a selective inhibitor of CKIδ, with an IC50 of 290 nM, and less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively. |
| In Vitro: | LH846 is a potent inhibitor of CKIδ, with an IC50 of 290 nM, less potently inhibits CKIα and CKIε, with IC50s of 2.5 μM and 1.3 μM, respectively, and has no effect on CK2. LH846 (3 or 10 μM) inhibits CKIδ-dependent phosphorylation of PER1 in HEK293T cells[1]. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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