MDI-2268|MDI2268|CAS 1609176-50-2|DC Chemicals

Cas No.:	1609176-50-2
Chemical Name:	2-hydrazinyl-2-oxo-N-(3-(trifluoromethoxy)benzyl)acetamide
Synonyms:	MDI2268
SMILES:	C(NCC1=CC=CC(OC(F)(F)F)=C1)(=O)C(NN)=O
Formula:	C₁₀H₁₀F₃N₃O₃
M.Wt:	277.203
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	MDI-2268 (MDI2268) is a small-molecule, in vivo-active inhibitor of plasminogen activator inhibitor type-1 (PAI-1), demonstrates excellent pharmacokinetics, potent activity against vitronectin-bound PAI-1 in vivo, and efficacy in murine model of venous thrombosis.
References:	References 1. Reinke AA, et al. J Biol Chem. 2018 Dec 3. pii: jbc.RA118.004885. doi: 10.1074/jbc.RA118.004885. View Related Products by Target Plasminogen Activator Inhibitor-1 (PAI-1)

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