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MHAPC-Chol

  Cat. No.:  DC36452  
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
MHAPC-Chol is a cationic cholesterol. MHAPC-Chol, as part of a lipoplex with DOPE, has been used for siRNA delivery and gene silencing in MCF-7 cells in a luciferase assay without affecting cell viability. It has also been used to deliver siRNA into mice via intravenous injection, resulting in MHAPC-chol accumulation in the liver.
Cas No.:
Chemical Name: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (3-((2-hydroxyethyl)(methyl)amino)propyl)carbamate
Synonyms: MHAPC-Chol
SMILES: C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCCN(C)CCO)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Formula: C34H60N2O3
M.Wt: 544.86
Cat. No. Product name Field of application
DC70000 Lysyllysyllysine Lysyllysyllysine is a cationic moietie that may be used in the construction of gene delivery vectors and DNA nanoparticles.
DC81110 N6-Hydroxynorvalylcarbamoyladenosine N6-Hydroxynorvalylcarbamoyladenosine (hn6A) (compound 1) is a nucleoside discovered in unfractionated tRNA from Thermodesulfobacterium commune. N6-Hydroxynorvalylcarbamoyladenosine is a modified nucleoside.
DC80069 3'-O-(2-Nitrobenzyl)-dTTP 3'-O-(2-Nitrobenzyl)-dTTP acts as a reversible terminator for DNA chain elongation. 3'-O-(2-Nitrobenzyl)-dTTP interacts with 9°N polymerase (exo-) A485L/Y409V, gets recognized and incorporated into the elongating DNA chain, thereby temporarily terminating the polymerase reaction. 3'-O-(2-Nitrobenzyl)-dTTP carries a 3'-O-(2-nitrobenzyl) blocking group, which can be removed by laser irradiation to regenerate the free 3'-OH− group and restore polymerase activity. 3'-O-(2-Nitrobenzyl)-dTTP is applicable in DNA sequencing studies.
DC80066 3'-O-(2-Nitrobenzyl)-dATP 3'-O-(2-Nitrobenzyl)-dATP is a reversible and photolabile DNA synthesis terminator. 3'-O-(2-Nitrobenzyl)-dATP incorporates into growing DNA strands to terminate synthesis in a base-specific manner. 3'-O-(2-Nitrobenzyl)-dATP undergoes efficient photolytic removal of its 3'-protecting group upon UV exposure to enable reinitiation of DNA synthesis. 3'-O-(2-Nitrobenzyl)-dATP supports development of the Base Addition Sequencing Scheme (BASS) via a complete stop-start DNA synthesis cycle.
DC80060 3-Chloropropan-1-amine hydrochloride 3-Chloropropan-1-amine hydrochloride is a PROTAC linker that can be used in the synthesis of PROTACs.
DC80050 3-(4-Bromophenyl)propanoic acid 3-(4-Bromophenyl)propanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.
DC80036 2-Bromo-LSD D-Tartrate 2-Bromo-LSD D-Tartrate is a blood-brain barrier-permeable 5-HT2A partial agonist and competitive partial antagonist. 2-Bromo-LSD D-Tartrate acts as both a potent partial agonist (with an EC50 of 0.81 nM for Gq dissociation) and a potent partial antagonist (with a KB of 0.18 nM for Gq dissociation) at the 5-HT2A receptor. 2-Bromo-LSD D-Tartrate exhibits partial agonist activity at multiple aminergic GPCRs, including 5-HT2A. 2-Bromo-LSD D-Tartrate lacks 5-HT2B agonist activity. 2-Bromo-LSD D-Tartrate induces dendritogenesis and spinogenesis. 2-Bromo-LSD D-Tartrate reverses the behavioral effects of chronic stress and increases active coping behaviors in mice.
DC80035 2-Bromo-5-Chloroterephthalic Acid 2-Bromo-5-Chloroterephthalic Acid (2-Bromo-5-chloroterephthalic acid) is a metal-organic framework (MOF).
DC80011 1-Nonadecanoin-2,3-acetyl 1-Nonadecanoin-2,3-acetyl is an acylglycerol.
DC80001 1-Heptanoyl-2,3-diacetyl 1-Heptanoyl-2,3-diacetyl is an acylglycerol.
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