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MRS-1845

  Cat. No.:  DC20220   Featured
Chemical Structure
544478-19-5
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More than 5000 active chemicals with high quality for research!
Field of application
MRS 1845 is a potent calcium channel protein inhibitor and inhibits capacitative Ca2+ influx in HL-60 cells (IC50 = 1.7 mM).
Cas No.: 544478-19-5
Synonyms: MRS-1845,MRS1845,MRS 1845
SMILES: CCOC(=O)C1=C(N(C(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)CC#C)C
Formula: C21H22N2O6
M.Wt: 398.41
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: MRS1845 is a Ca2+ channel blocker with relative specificity for store-operated calcium entry (SOCE) channels[1].
Target: Ca2+ channel[1]
References: [1]. Lee C, et al. Store-operated calcium channel inhibition attenuates neutrophil function and postshock acute lung injury. J Trauma. 2005 Jul;59(1):56-63.
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