Cas No.: | 1847461-43-1 |
Chemical Name: | Mobocertinib free base |
Synonyms: | AP-32788,AP32788,AP 32788,TAK 788,TAK788,TAK-788 |
SMILES: | O=C(OC(C)C)C1C(C2C3C=CC=CC=3N(C)C=2)=NC(NC2C(OC)=CC(N(C)CCN(C)C)=C(NC(=O)C=C)C=2)=NC=1 |
Formula: | C32H39N7O4 |
M.Wt: | 585.71 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Publication: | [1]. Francois Gonzalvez, et al. Abstract 2644: AP32788, a potent, selective inhibitor of EGFR and HER2 oncogenic mutants, including exon 20 insertions, in preclinical models. April 16-20, 2016; New Orleans, LA. |
Description: | Mobocertinib is a potent epidermal growth factor receptor (EGFR) inhibitor and an antineoplastic agent, extracted from patent WO2019222093A1, compound A[1][2]. |