Cas No.: | 4550-72-5 |
Synonyms: | NSC15364,NSC15364 |
SMILES: | C1=CC(=CC=C1N)NC(=O)NC2=CC=C(C=C2)N |
Formula: | C13H14N4O |
M.Wt: | 242.28 |
Purity: | >98% |
Description: | NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1]. |
In Vitro: | Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1]. |
References: | [1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003. |