NSC260594|CAS 906718-66-9|DC Chemicals

Cas No.:	906718-66-9
Chemical Name:	4-[(1-methyl-6-nitroquinolin-4-ylidene)amino]-N-[4-[(1-methylpyridin-4-ylidene)amino]phenyl]benzamide
Synonyms:	NSC 260594;NSC260594;NSC-260594
SMILES:	C(NC1=CC=C(/N=C2/C=CN(C)C=C/2)C=C1)(=O)C1=CC=C(/N=C2\C3=C(N(C)C=C\2)C=CC([N+]([O-])=O)=C3)C=C1
Formula:	C₂₉H₂₄N₆O₃
M.Wt:	504.55
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	References 1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25. 2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222. View Related Products by Target HIV

Description:

NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ); specifically blocks HIV-1 RNA encapsidation, binds to HIV-1 gRNA and exhibits potent antiviral activity; NSC260594 also is a small molecule inhibitor of the Escherichia coli condensin MukBEF, affects MukB directly.

References:

References 1. Ingemarsdotter CK, et al. Retrovirology. 2018 Mar 14;15(1):25. 2. Zhao H, et al. ACS Infect Dis. 2018 Oct 22. doi: 10.1021/acsinfecdis.8b00222. View Related Products by Target HIV

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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