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PDM2

  Cat. No.:  DC10904   Featured
Chemical Structure
688348-25-6
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More than 5000 active chemicals with high quality for research!
Field of application
PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 688348-25-6
Synonyms: PDM-2,PDM2,PDM 2,688348-25-6
SMILES: Clc1ccc(cc1)\C=C/c1cc(Cl)cc(Cl)c1
Formula: C14H9Cl3
M.Wt: 283.6
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.
Target: Ki: 1.2±0.4 nM(AhR)[1]
In Vitro: PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR[1].
References: [1]. de Medina P, et al. Synthesis and biological properties of new stilbene derivatives of resveratrol as new selective aryl hydrocarbon modulators. J Med Chem. 2005 Jan 13;48(1):287-91.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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