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PE 154

  Cat. No.:  DC33249   Featured
Chemical Structure
1192750-33-6
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More than 5000 active chemicals with high quality for research!
Field of application
PE 154 are known to associate with β-amyloid plaques, and histological co-localization of AChE and Ab peptides is well established in Alzheimer’s disease. PE-154 is a fluorescent inhibitor of both AChE and BChE with IC50 values of 280 pM and 16 nM. PE-154 stains Aβ plaques in both rodent and human tissue samples, and does not cross react with phospho-tau.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1192750-33-6
Chemical Name: PE 154
Synonyms: PE 154;2-(1,2,3,4-Tetrahydro-9-acridinyl)hydrazide-4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid;4-[[[7-(Diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid 2-(1,2,3,4-tetrahydro-9-acridinyl)hydrazide;N'-(1,2,3,4-Tetrahydroacridine-9-yl)-2-[4-[[[2,4-dioxo-7-(diethylamino)-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]phenyl]acetohydrazide;2-[4-[[7-(Diethylamino)-4-hydroxy-2-oxochromen-3-yl]methylideneamino]phenyl]-N'-(1,2,3,4-tetrahydroa;PE154;PE 154
SMILES: O1C(C(/C=N/C2C=CC(=CC=2)CC(NNC2C3C=CC=CC=3N=C3CCCCC3=2)=O)=C(C2C=CC(=CC1=2)N(CC)CC)O)=O
Formula: C35H35N5O4
M.Wt: 589.68350815773
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_15560_DC33249_1192750-33-6
COA
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