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PROTAC IRAK4 degrader-1

  Cat. No.:  DC28609  
Chemical Structure
2360533-90-8
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More than 5000 active chemicals with high quality for research!
Field of application
PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes <20%, >20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2360533-90-8
Formula: C44H39F3N12O7
M.Wt: 904.85
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_12661_DC28609_2360533-90-8
COA
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Cat. No. Product name Field of application
DC47585 PROTAC CDK9 ligand-1 PROTAC CDK9 ligand-1 is a CDK9 ligand that can be used in the synthesis of PROTACs.
DC47584 PROTAC BRD4 ligand-2 PROTAC BRD4 ligand-2 is a ligand for target BRD4 protein for PROTAC CFT-2718.
DC47372 Bromo-C10-OBn Bromo-C10-OBn is a PROTAC linker that can be used in the synthesis of PROTACs.
DC47371 1-Bromo-6-chlorohexane 1-Bromo-6-chlorohexane is a PROTAC linker can be used in the synthesis of PROTACs.
DC47370 Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47369 Propargyl-PEG2-CH2COOH Propargyl-PEG2-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
DC47319 Dovitinib-RIBOTAC Dovitinib RIBOTAC is a targeted RNA degrader that cleaves pre-miR-21 with enhanced potency and selectivity.
DC47213 L-Homopropargylglycine hydrochloride L-Homopropargylglycine hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. L-homopropargylglycine hydrochloride is an amino acid analog of methionine containing an alkyne moiety that can undergo a classic click chemical reaction with azide containing Alexa Fluor.
DC47212 Boc-bipiperidine-ethynylbenzoic acid Boc-bipiperidine-ethynylbenzoic acid is an Alkyl/ether-based PROTAC linker can be used in the synthesis of ARD-61.
DC47193 OICR-9429-N-C2-NH2 OICR-9429-N-C2-NH2 is a ligand for Wd40 repeat domain protein 5 (WDR5) extracted from patent WO2019246570A1, intermediate 2. OICR-9429-N-C2-NH2 can be used in the synthesis of PROTACs.
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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