Cas No.: | 150404-10-7 |
Chemical Name: | 3-(3,4-Dihydroxy-2-nitrophenyl)-1-phenyl-2-propen-1-one |
SMILES: | C(C1=CC=CC=C1)(=O)/C=C/C1=CC=C(O)C(O)=C1[N+]([O-])=O |
Formula: | C15H11NO5 |
M.Wt: | 285.255 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | QO IIR is a reversible, tight-binding inhibitor inhibitor of catechol-O-methyltransferase (COMT) with IC50 of 320 nM; fully reverses the reserpine-induced catalepsy in vivo, demonstrates behavioural and neurochemical effects in reserpinized rats treated with LD/CD. |