Cas No.: | 1214672-15-7 |
Chemical Name: | 2-amino-3-methyl-N-[2-(morpholin-4-yl)ethyl]pentanamide dihydrochloride |
SMILES: | Cl.Cl.NC(C(C)CC)C(NCCN1CCOCC1)=O |
Formula: | C12H27Cl2N3O2 |
M.Wt: | 316.267681360245 |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | (Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist[1]. |
References: | [1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500. |