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Home > Molecular Glues

Schisandrin C

  Cat. No.:  DCW-009   Featured
Chemical Structure
61301-33-5
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More than 5000 active chemicals with high quality for research!
Field of application
Schisandrin C (Schizandrin-C) is a phytochemical lignan derived from Schizandra chinensis, known for its diverse biological activities, including anticancer, anti-inflammatory, and antioxidant effects. Functioning as a molecular glue, Schisandrin C holds potential for research in cancer, Alzheimer’s disease, and liver diseases. It also induces cell apoptosis.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 61301-33-5
Chemical Name: Schisandrin C
Synonyms: WUWEIZISU C;,8-dimethyl-;cycloocta(1,2-f:3,4-f’)bis(1,3)benzodioxole6,7,8,9-tetrahydro-1,13-dimethoxy-7;(6R,7S,13aS)-5,6,7,8-Tetrahydro-13,14-dimethoxy-6,7-dimethylcycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole;(S)-(-)-Schisandrin C;SCHIZANDRIN C;Schisandrin C;Schisandrin-C;Schizandrin-C;Wuweizisu-C;(-)-Wuweizisu C;C8754W6B3G;SureCN2406629;N2559;C10893;A14756;66138-32-7;NCGC00385072-01;[1,3]Dioxolo[4'',5'']benzo[1'',2'':3',4']cycloocta[1',2':4,5]benzo[1,2-d]-1,3-dioxole, 5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-;Schisandrin dervative;95152-94-6;Schizandrin-C;Wuweizisu-C;NSC609258;CCG-268455;schisandrinC;LS-14945;Schisandrin C, >=98% (HPLC);61301-33-5;R-(+)-Wuweizisu C;AC-34835;SCHEMBL12280310;MFCD00272170;NCGC00385072-01_C22H24O6_13,14-Dimethoxy-6,7-dimethyl-5,6,7,8-tetrahydro[1,3]benzodioxolo[5',6':3,4]cycloocta[1,2-f][1,3]benzodioxole;[1,3]Dioxolo[4'',5'']benzo[1'',2'':3',4']cycloocta[1',2':4,5]benzo[1,2-d]-1,3-dioxole,5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-;NSC-609258;DTXSID101317497;Schisandrin derivative;3,22-dimethoxy-12,13-dimethyl-5,7,18,20-tetraoxapentacyclo[13.7.0.02,10.04,8.017,21]docosa-1(22),2,4(8),9,15,17(21)-hexaene;(6R,7S,13aS)-5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole;Q27108563;CS-3664;UNII-C8754W6B3G;CHEMBL437412;AKOS015897177;AC1L9DW8;SCHEMBL2406629;Cycloocta(1,2-f:3,4-f')bis(1,3)benzodioxole 5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-, (6R,7S,13aS)-;CHEBI:10044;HY-N0690;CYCLOOCTA(1,2-F:3,4-F')BIS(1,3)BENZODIOXOLE, 5,6,7,8-TETRAHYDRO-13,14-DIMETHOXY-6,7-DIMETHYL-, (6R,7S,13AS)-;DA-67487
SMILES: O1C([H])([H])OC2=C1C([H])=C1C(=C2OC([H])([H])[H])C2=C(C3=C(C([H])=C2C([H])([H])[C@@]([H])(C([H])([H])[H])[C@@]([H])(C([H])([H])[H])C1([H])[H])OC([H])([H])O3)OC([H])([H])[H]
Formula: C22H24O6
M.Wt: 384.4224
Purity: >98%, Standard References Grade
Sotrage: 4°C for 1 year, -20°C for more than 2 years
Description: For the detailed information of Schisandrin C, the solubility of Schisandrin C in water, the solubility of Schisandrin C in DMSO, the solubility of Schisandrin C in PBS buffer, the animal experiment（test） (test) of Schisandrin C, the cell expriment (test) of Schisandrin C, the in vivo, in vitro and clinical trial test of Schisandrin C, the EC50, IC50,and Affinity of Schisandrin C,, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC60864 D927 (DS11252927) D927 is a molecular glue and promotes glucose uptake in the absence of insulin. D927 also increases the affinity of RAS binding to PI3Kα by ~500-fold. In vivo, D927 mimicks the effects of insulin and rapidly lowers blood glucose concentrations.
DC60863 D223 (DS02312223) D223 is a molecular glue and promotes glucose uptake in the absence of insulin. D223 also increases the affinity of RAS binding to PI3Kα by ~500-fold.
DC60858 LC-04-045 LC-04-045 is a leading NEK7 molecular glue degrader with DC50 of 7 nM and Dmax of 90 % in MOLT-4 cells. LC-04-045 displays high selectivity for NEK7 across the proteome.
DC60852 PVTX-405 PVTX-405 is a potent, effective, highly selective, and orally efficacious IKZF2 molecular glue degrader with DC50 of  0.7 nM. PVTX-405 in combination with anti-PD1 or anti-LAG3 significantly increases animal survival compared to anti-PD1 or anti-LAG3 alone.
DC60837 MGD-28 MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro efficacy against various hematological cancer cell lines. It induces degradation of Ikaros family zinc finger proteins 1, 2, and 3 (IKZF1/2/3) and casein kinase 1 alpha (CK1α) with nanomolar potency via a Cullin-cereblon (CRBN) dependent pathway. Compared to lenalidomide and pomalidomide, MGD-28 achieves deeper, faster, and more potent degradation of these neosubstrates. Additionally, MGD-28 exhibits broad antiproliferative activity in multiple solid malignancies and shows preferential cytotoxicity toward multiple myeloma patient-derived cells at various disease stages.
DC67413 MRT-23227
DC67412 MRT-3486 MRT-3486 (Compound 5) is a cereblon-based NEK7 molecular glue degrader. MRT-3486 can be used for autoinflammatory diseases research.
DC67411 MRT-7612
DC67410 MRT-10350
DC67407 IKZF1-degrader-1 IKZF1-degrader-1 (Compound 9-B) is a highly potent molecular glue that achieves sub-nanomolar degradation of IKZF1 (DC50 = 0.134 nM), demonstrating significant therapeutic potential for targeting IKZF1-dependent malignancies.
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