Senkyunolide I|cas 94596-28-8|Supplied by DC Chem

Cas No.:	94596-28-8
SMILES:	O=C1O/C(C2=C1[C@@H](O)[C@H](O)CC2)=CCCC
Formula:	C₁₂H₁₆O₄
M.Wt:	224.1
Purity:	>98%, Standard References Grade
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:	Senkyunolide I, isolated from Ligusticum chuanxiong Hort, is an anti-migraine compound. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3[1][2].
References:	[1]. Wang YH, et al. Effect and mechanism of senkyunolide I as an anti-migraine compound from Ligusticum chuanxiong. J Pharm Pharmacol. 2011 Feb;63(2):261-6. [2]. Hu Y, et al. Senkyunolide I protects rat brain against focal cerebral ischemia-reperfusion injury by up-regulating p-Erk1/2, Nrf2/HO-1 and inhibiting caspase 3. Brain Res. 2015 Apr 24;1605:39-48.

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