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BAY 73-1449

  Cat. No.:  DC42502  
Chemical Structure
693790-96-4
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More than 5000 active chemicals with high quality for research!
Field of application
BAY 73-1449 is a selective antagonist of prostacyclin IP receptor, with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG. BAY 73-1449 can be used in the research of lowering blood pressure.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 693790-96-4
Synonyms: BAY 73-1449
SMILES: O=C(O)[C@@H](CC1=CC=CC=C1)NC2=NC=NC(C3=CC=C(OCC4=CC=CC=C4)C=C3)=C2
Formula: C26H23N3O3
M.Wt: 425.48
Sotrage: Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
MSDS
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MSDS_26130_DC42502_693790-96-4
COA
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Cat. No. Product name Field of application
DC42503 Taprenepag isopropyl Taprenepag isopropyl is a highly selective EP2 receptor agonist.
DC47374 Aligeron Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties.
DC47373 CAY10580 CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM).
DC47183 Aganepag isopropyl Aganepag isopropyl (AGN-210961) is an EP2 agonist.
DC47172 15-Keto latanoprost 15-Keto latanoprost is a metabolite of Latanoprost, which is an ocular hypotensive agent.
DC47127 Pexopiprant Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2),Ki ＜ 100nM. Pexopiprant can be used in studies of asthma.
DC47089 Treprostinil palmitil Treprostinil palmitil (TP) is the prodrug of DP1 and EP2 agonist, Treprostinil (UT-15), whose EC50 values were 0.6 and 6.2 nM, respectively. Treprostinil palmitil is a pure prodrug and possesses no inherent binding to G-protein coupled receptors including prostanoid receptors.
DC46853 BGC-20-1531 free base BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKb of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache.
DC46564 Bimatoprost D5 Bimatoprost D5 (AGN 192024 D5) is a deuterium labeled Bimatoprost. Bimatoprost is a prostaglandin analog and is a topical hypotensive agent frequently used for treating ocular hypertension and glaucoma. Bimatoprost also has an antiadipogenic effect.
DC45799 TCS 2510 TCS 2510 is a selective EP4 agonist. TCS 2510 can be used for the research of metabolic diseases.
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