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CCT373566

  Cat. No.:  DC73095   Featured
Chemical Structure
2378853-66-6
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More than 5000 active chemicals with high quality for research!
Field of application
CCT373566 is a highly potent, in vivo active BCL6 degrader, demonstrating an IC50 of 2.2 nM in TR-FRET assays and a DC50 of 0.7 nM in cellular BCL6 degradation assays.
Cas No.: 2378853-66-6
Chemical Name: [1,​4]​Oxazepino[2,​3-​c]​quinolin-​6(7H)​-​one, 10-​[[5-​chloro-​2-​[(3R,​5S)​-​3-​hydroxy-​5-​methyl-​1-​piperidinyl]​-​4-​pyrimidinyl]​amino]​-​2-​cyclopropyl-​3,​3-​difluoro-​1,​2,​3,​4-​tetrahydro-​7-​methyl-​, (2S)​-
Synonyms: CCT373566
SMILES: C12=C(C3=CC(NC4=NC(N5C[C@@H](C[C@H](C)C5)O)=NC=C4Cl)=CC=C3N(C)C1=O)N[C@H](C(CO2)(F)F)C1CC1
Formula: C26H29ClF2N6O3
M.Wt: 547.00
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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