- Chemicals for Life Science -

Alternate Text

To enhance service speed and avoid tariff delays, we've opened a US warehouse. All US orders ship directly from our US facility.

Home > Products > Novel inhibitors

CD73-IN-4

Cat. No.: DC42557

Chemical Structure

2216764-29-1

For research use only. We do not sell to patients.

We match the best price and quality on market.
Email:order@dcchemicals.com sales@dcchemicals.com
Tel:+86-021-58447131

Get Quotation Now

We are official vendor of:

More than 5000 active chemicals with high quality for research!

Field of application

CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology.

Chemicals Properties Biological activity COA & MSDS Related products Datasheet

Cas No.:	2216764-29-1
Synonyms:	CD73-IN-4
SMILES:	O[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C3=C(C=N2)C(NC4CCCC4)=NC(Cl)=N3)COCP(O)(O)=O
Formula:	C₁₆H₂₃ClN₅O₇P
M.Wt:	463.81
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

MSDS

TITLE	DOWNLOAD
MSDS_26185_DC42557_2216764-29-1

COA

LOT NO.	DOWNLOAD

Cat. No.	Product name	Field of application
DC47767	N6-Benzyl-5'-ethylcarboxamido adenosine	N6-Benzyl-5'-ethylcarboxamido adenosine is a selective A3 adenosine receptor agonist.
DC47766	Adenosine receptor antagonist 1	Adenosine receptor antagonist 1 is a A2aR-selective antagonist with an IC50 of 0.29 nM and displays 14-fold more selective for A2aRthan A2bR.
DC47765	hA3AR agonist 1	hA3AR agonist 1 is a potent human A3 adenosine receptor (hA3AR) agonist with a Ki value of 2.40 nM.
DC47235	Binodenoson	Binodenoson (MRE-0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.
DC47196	UK-432097	UK-432097 is a highly potent and selective A2AAR agonist with a pKi of 8.4 for human A2AAR. UK-432097 has anti-inflammatory and anti-aggregatory properties. UK-432097 has the potential for COPD (Chronic Obstructive Pulmonary Disease) research.
DC47006	A2B receptor antagonist 2	A2B receptor antagonist 2 (compound 18) is an adenosine receptor A2B antagonist, with Ki values of 2.30 μM, 6.8 μM and 3.44 μM for rA1, rA2A and hA2B, respectively.
DC46391	PSB-10 hydrochloride	PSB-10 hydrochloride is a potent and selective antagonist of human adenosine A3 receptor (A3AR), with a Ki of 0.44 nM. PSB-10 hydrochloride shows more than 800-fold selectivity for hA3 over rA1, rA2A, hA1, hA2A and hA2B receptors (Ki=805, 6040, 1700, 2700, 30000 nM, respectively). PSB-10 hydrochloride produces thermal hyperalgesia in mice.
DC45783	Norisoboldine hydrochloride	Norisoboldine hydrochloride is an orally active natural aryl hydrocarbon receptor (AhR) agonist. Norisoboldine hydrochloride, as a major isoquinoline alkaloid present in Radix Linderae, can be used for the research of Rheumatoid arthritis and Ulcerative colitis.
DC45528	5'-N-Ethylcarboxamidoadenosine (NECA)	5'-N-Ethylcarboxamidoadenosine (NECA, 5'-(N-Ethylcarboxamido)adenosine, Adenosine-5'N-ethylcarboxamide, 5'-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5'-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54)), and blocking activation of the JNK-MAPK pathway.
DC45384	LUF6096	LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury.

X

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.

Site Map|Privacy PolicyCopyright © 2018-2020 All Rights Reserved. Technical Support:KuuJia