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DEG-77

  Cat. No.:  DC74572   Featured
Chemical Structure
3032265-06-5
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More than 5000 active chemicals with high quality for research!
Field of application
DEG-77 is a cereblon-dependent degrader targeting IKZF2 and casein kinase 1α (CK1α). It effectively blocks cell growth and delays leukemia progression in both murine and human acute myeloid leukemia (AML) mouse models.
Cas No.: 3032265-06-5
Chemical Name: DEG-77
SMILES: O=C1C2=CC=C(C=C2CN1C3CCC(NC3=O)=O)NC(C4=CC5=C(OC4)C(OC)=CC=C5)=O
Formula: C24H21N3O6
M.Wt: 447.44
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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