Cas No.: | 6674-45-9 |
Chemical Name: | Diguanosine 5′-triphosphate |
SMILES: | O=C1C2=C(NC(N)=N1)N([C@]3([H])O[C@@H]([C@H]([C@H]3O)O)COP(OP(OP(OC[C@H]4O[C@](N5C6=C(C(N=C(N6)N)=O)N=C5)([H])[C@@H]([C@@H]4O)O)(O)=O)(O)=O)(O)=O)C=N2 |
Formula: | C20H27N10O18P3 |
M.Wt: | 788.41 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase[1]. Diguanosine 5′-triphosphate is a virus-specific oligonucleotide, can be used to prime reovirus transcription and inhibit RNA methylation[2]. |
References: | [1]. J J Liu, et al. Purification and properties of GTP:GTP guanylyltransferase from encysted embryos of the brine shrimp Artemia. J Biol Chem [2]. M Yamakawa, et al. Priming of reovirus transcription by GppppG and formation of CpG(5')GpC. Proc Natl Acad Sci U S A. 1982 Oct;79(20):6142-6. |