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DS17

  Cat. No.:  DC67343   Featured
Chemical Structure
For research use only. We do not sell to patients.
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More than 5000 active chemicals with high quality for research!
Field of application
DS17 is a high-efficiency molecular glue degrader that specifically induces the degradation of cyclin K, demonstrating remarkable potency with an EC50 of 13 nM. By exploiting the ubiquitin-proteasome system, DS17 effectively eliminates cyclin K, a critical regulator of transcription and cell cycle progression, positioning it as a valuable tool in cancer research and drug discovery.
Cas No.:
Chemical Name: DS17
SMILES: CC(C)N(C=N1)C2=C1C(NCC3=NC(C=C(Cl)C(Cl)=C4)=C4N3)=NC(N[C@H](CC)CO)=N2
Formula: C20H24Cl2N8O
M.Wt: 463.36
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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