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  Cat. No.:  DC42616   Featured
Chemical Structure
445222-91-3
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More than 5000 active chemicals with high quality for research!
Field of application
Novel inhibitor of MuRF1, attenuating skeletal muscle atrophy and dysfunction in cardiac cachexia
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 445222-91-3
Chemical Name: MuRF1-IN-1
Synonyms: MuRF1-IN-1;Oprea1_487101;RSC004160;STK863604;ST071760;1'-Methyl-2',5-dioxo-5,6,7,8-tetrahydro-2-aminospiro[4H-1-benzopyran-4,3'-indoline]-3-carbonitrile;2'-amino-3'-cyano-1-methyl-1,3,5',6',7',8'-hexahydro-2,5'-dioxospiro[2H-indol-3,4'-(4'H)-chromene];2-amino-1'-methyl-2',5-dioxo-1',2',5,6,7,8-hexa-hydrospiro[chromene-4,3'-indole]-3-carbonitrile;2-amino-1'-methyl-2',5-dioxo
SMILES: O1C(=C(C#N)C2(C(N(C)C3C=CC=CC2=3)=O)C2C(CCCC1=2)=O)N
Formula: C18H15N3O3
M.Wt: 321.330003976822
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Novel inhibitor of MuRF1, attenuating skeletal muscle atrophy and dysfunction in cardiac cachexia
References: [1]. Bowen TS, Adams V, Werner S, et al. Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia. J Cachexia Sarcopenia Muscle. 2017 Dec;8(6):939-953.
MSDS
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MSDS_26246_DC42616_445222-91-3
COA
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Cat. No. Product name Field of application
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