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Flurocitabine

  Cat. No.:  DC47992  
Chemical Structure
37717-21-8
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More than 5000 active chemicals with high quality for research!
Field of application
Flurocitabine is a fluorinated anlydride analog of cytosine arabinoside, partially hydrolysecl in vivo into two active antitumor substances (arabinosyl-tluorocytosine (ara-FC) and arabinosyl-fluorouracil (ara-FU)). Flurocitabine has antitumor activity during phase I studies in acute leukemia and solid tumors.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 37717-21-8
Chemical Name: Flurocitabine
Formula: C9H10FN3O4
M.Wt: 243.19
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC73210 TH7528 TH7528 is a SAMHD1 inhibitor with IC50 of 4.5 μM/2.8 μM/2.6 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively.
DC73203 DI-87 DI-87 ((R)-DI-87) is a highly potent, specific, orally bioavailable deoxycytidine kinase (dCK) inhibitor with IC50 of 3.15 nM.
DC72019 Fludarabine triphosphate trisodium Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine, is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
DC44975 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
DC41008 Fludarabine triphosphate Fludarabine triphosphate (F-ara-ATP), the cytotoxic metabolite of Fludarabine phosphate, inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis.
DC7762 RX-3117 RX-3117 is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity.
DC76243 UnyLinker 12 TEA UnyLinker 12 TEA is a universal linker that can be used to synthesize oligoribonucleotides.
DC76242 Ribavirin 5'-monophosphate dilithium Ribavirin 5'-monophosphate dilithium is an active form of ribavirin that inhibits IMP dehydrogenase, and ribavirin itself is a broad-spectrum antiviral agent.
DC76241 Pseudouridine 5'-OTBDPS Pseudouridine 5'-OTBDPS (5-(5-O-TBDPS-β-D-ribofuranosyl)uracil) is an intermediate of Pseudouridine. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
DC76240 N-Acetyl-2',3'-acetyl-guanosine N-Acetyl-2', 3'-Acetyl-Guanosine is a modified guanosine nucleoside.
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