Cas No.: | 146478-73-1 |
Chemical Name: | 2-Pentenamide,4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5S,7R,8R)-4,5,8-trihydroxy-5-methyl-1,6-dioxaspiro[2.5]oct-7-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-,(2Z,4S)- |
SMILES: | CC(=O)O[C@@H](C)\C=C/C(=O)N[C@H]1[C@@H](C)O[C@@H](C\C=C(/C)\C=C\[C@@H]2[C@@H](O)[C@]3(OC3)[C@@H](O)[C@@](O)(C)O2)[C@@H](C)C1 |
Formula: | C27H41NO9 |
M.Wt: | 523.61574 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1]. |
In Vitro: | FR901465 prolongs the life of mice bearing murine ascitic tumor P388 leukemia (T/C values 127% for FR901465 in mice bearing murine ascitic tumors[1]. |
References: | [1]. H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. [2]. H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. [3]. Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT |