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GSK-3/CDK5/CDK2-IN-1

  Cat. No.:  DC44017  
Chemical Structure
395074-72-3
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More than 5000 active chemicals with high quality for research!
Field of application
GSK-3/CDK5/CDK2-IN-1, an imidazole derivative, is an inhibitor of cdk5, cdk2, and GSK-3 extracted from patent WO2002010141A1, example 9a. GSK-3/CDK5/CDK2-IN-1 can be used for the research of cancer, and neurodegenerative diseases.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 395074-72-3
Chemical Name: GSK-3/CDK5/CDK2-IN-1
SMILES: O=C(NC1=CN([C@H]2C[C@@H](NC(C)=O)C2)C=N1)CC3=CC=C4C=CC=CC4=C3
Formula: C21H22N4O2
M.Wt: 362.42
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_27699_DC44017_395074-72-3
COA
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Cat. No. Product name Field of application
DC47707 CDK/HDAC-IN-1 CDK/HDAC-IN-1 shows remarkable CDK2/4/6 and HDAC6 inhibitory activity of IC50 = 60.9 ± 2.9, 276 ± 22.3, 27.2 ± 4.2, and 128.6 ± 0.4 nM, respectively.
DC47706 CDK2-IN-7 CDK2-IN-7 is a CDK2 inhibitor for treating cancer (IC50 < 50 nM).
DC47705 JH-XVI-178 JH-XVI-178 is a highly potent and selective inhibitor of CDK8/19 that displays low clearance and moderate oral pharmacokinetic properties.
DC47704 CDK9-IN-12 CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.
DC47236 Cirtuvivint Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor. Cirtuvivint can be used for solid tumors research.
DC47205 Eltenac Eltenac, a non-steroidal anti-inflammatory drug (NSAID), is a COX inhibitor. Eltenac shows IC50 of 0.03 μM for both COX-1 and COX-2 in isolated human whole blood.
DC47130 CDK5-IN-1 CDK5-IN-1, a potent CDK5 inhibitor, is against CDK5 activity less than 10 nM. CDK5-IN-1 is used for kidney diseases research.
DC47109 Cimpuciclib Cimpuciclib is a cyclin-dependent kinase(CDK) inhibitor and antineoplastic.
DC47043 Ocarocoxib Ocarocoxib, a potent COX-​2 (cyclooxygenase-​2) inhibitor, is a non-steroidal anti-inflammatory for veterinary use.
DC46945 Avotaciclib Avotaciclib (BEY1107) is an orally active cyclin dependent kinase 1 (CDK1) inhibitor. Avotaciclib can be used for the research of cancer.
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Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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