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Hdl376

  Cat. No.:  DCC2512   Featured
Chemical Structure
147751-31-3
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More than 5000 active chemicals with high quality for research!
Field of application
HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 147751-31-3
Chemical Name: 1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thiourea
Synonyms: Thiourea,N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)-;N-(5-Chloro-2-methylphenyl)-N'-isobutylcarbamimidothioic acid;methanethiol, 1-[(5-chloro-2-methylphenyl)amino]-1-[(2-methylpropyl)imino]-, (Z)-;N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)carbamimidothioic acid;1-(5-chloro-2-methylphenyl)-3-(2-methylpropyl)thiourea;EN300-25750695;AKOS003713256;N-(5-CHLORO-2-METHYLPHENYL)-N'-(2-METHYLPROPYL)-THIOUREA;N-(5-chloro-2-methylphenyl)-N'-(2methylpropyl)thiourea;PD074108;Z45770691;B4KLE87R9D;CHEMBL199418;SCHEMBL9053597;147751-31-3;1-(5-chloro-2-methylphenyl)-3-isobutylthiourea;Thiourea, N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)-;HDL376;BDBM50175261;starbld0005445;SDZ-HDL-376;UNII-B4KLE87R9D;N-(5-chloro-2-methylphenyl)-N'-(2-methylpropyl)thiourea
SMILES: CC(CNC(NC1=CC(Cl)=CC=C1C)=S)C
Formula: C12H17ClN2S
M.Wt: 256.79478
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
Cat. No. Product name Field of application
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DC75868 AZ14133346 AZ14133346 (compound 36) is a potent and selective inhibitor of EGFR Exon20 insertions, with the IC50 of 85 nM. AZ14133346 plays an important role in cancer research.
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DC75641 GENZ-644282 TFA salt Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325 PSMA-617 TFA PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
DC75202 Fosaprepitant free acid Fosaprepitant, also known as MK0517, is an antiemetic drug, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. Fosaprepitant is a weak inhibitor of CYP3A4, and aprepitant, the active moiety, is a substrate, inhibitor, and inducer of CYP3A4
DC74748 O4I4 O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
DC74684 ZH8667 ZH8667 is a trace amine-associated receptor 1 (TAAR1)–Gs agonist.
DC74646 EB-PSMA-617 EB-PSMA-617 is an Evans blue-modified prostate-specific membrane antigen (PSMA) 617 ligand for making 177Lu-EB-PSMA, which is potential useful for Metastatic Castration-Resistant Prostate Cancer.
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