JNJ-40355003|CAS 1394894-41-7|DC Chemicals

Cas No.:	1394894-41-7
Chemical Name:	1-Piperazinecarboxamide, 4-((3-(4-chlorophenoxy)phenyl)methyl)-N-3-pyridinyl-
Synonyms:	CHEMBL2164602;JNJ40355003;JNJ-40355003;HY-18013;CS-0007150;SCHEMBL1758816;UNII-Z0O8PGE4TB;DA-54546;Q27893050;Z0O8PGE4TB;compound 23 [PMID: 24900385];BDBM50394620;4-(3-(4-Chlorophenoxy)benzyl)-N-(pyridin-3-yl)piperazine-1-carboxamide;1394894-41-7;AKOS040748632;1-Piperazinecarboxamide, 4-((3-(4-chlorophenoxy)phenyl)methyl)-N-3-pyridinyl-;GTPL9050
SMILES:	ClC1C=CC(=CC=1)OC1=CC=CC(=C1)CN1CCN(C(NC2C=NC=CC=2)=O)CC1
Formula:	C₂₃H₂₃ClN₄O₂
M.Wt:	422.907324075699
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
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DC75865	TI17	TI17 represents a novel class of targeted anticancer agents that specifically disrupt DNA damage repair mechanisms in malignant cells.
DC75816	Nisoxetine	Nisoxetine acts as a highly selective and potent noradrenaline transporter (NET) antagonist, exhibiting a binding affinity (Kd) of 0.76 nM. In addition to its antidepressant properties, nisoxetine functions as a local anesthetic by inhibiting voltage-gated sodium channels. This dual pharmacological activity makes it a compound of interest for both neurological and pain management research.
DC75641	GENZ-644282 TFA salt	Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325	PSMA-617 TFA	PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
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DC74748	O4I4	O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
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