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dCK1α-2

  Cat. No.:  DC67364   Featured
Chemical Structure
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More than 5000 active chemicals with high quality for research!
Field of application
dCK1α-2 is an orally bioavailable molecular glue degrader targeting CK1α, a key regulator of p53 pathway signaling. This compound demonstrates robust in vivo anti-tumor activity in murine models while upregulating expression of p53-associated genes, highlighting its dual mechanism of action.
Cas No.:
Chemical Name: dCK1α-2
Synonyms: LC-05-004
SMILES: O=C1N([C@@H]2C(NC(CC2)=O)=O)CC3=C1C=CC(C4=NC5=C(Cl)C(CN6CCOCC6)=NN5C=C4)=C3
Formula: C24H23ClN6O4
M.Wt: 494.93
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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