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ML202

  Cat. No.:  DC42647   Featured
Chemical Structure
1221186-52-2
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More than 5000 active chemicals with high quality for research!
Field of application
ML202 represents a selective allosteric modulator of human pyruvate kinase M2 (hPK-M2) that specifically enhances phosphoenolpyruvate (PEP) binding cooperativity without significantly affecting adenosine diphosphate (ADP) binding kinetics.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1221186-52-2
Chemical Name: 4,6-Dihydro-6-[(3-methoxyphenyl)methyl]-4-methyl-2-(methylsulfinyl)-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
Synonyms: ML 202, ML202, ML-202
SMILES: O=C1N(CC4=CC=CC(OC)=C4)N=CC2=C1N(C)C3=C2SC(S(C)=O)=C3
Formula: C18H17N3O3S2
M.Wt: 387.48
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
MSDS
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MSDS_26277_DC42647_1221186-52-2
COA
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Cat. No. Product name Field of application
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DC75641 GENZ-644282 TFA salt Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
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