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Paprotrain

  Cat. No.:  DC43625   Featured
Chemical Structure
57046-73-8
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More than 5000 active chemicals with high quality for research!
Field of application
Reversible, non-ATP competitive inhibitor of mitotic kinesin-like protein 2 (MKLP-2)
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 57046-73-8
Chemical Name: Paprotrain
Synonyms: Paprotrain;(Z)-2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-indol-3-yl)-3-pyridin-3-yl-acrylonitrile;1h-i;2-(3-indolyl)-2-oxo acetyl chloride;2-indol-3-yl-2-oxoacetyl chloride;2-indol-3-yl-3-pyridin-3-yl-acrylonitrile;3-indoleglyoxyl chloride;3-Indoleglyoxylyl chloride;3-indolylglyoxalyl chloride;515205_ALDRICH;AC1L3IY9;AC1Q3G3N;Indole-3-glyoxyloyl chloride;Indole-3-Glyoxylyl Chloride;(alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile;(Z)-2-(1H-indol-3-yl)-3-pyridin-3-ylprop-2-enenitrile;BDBM50140923;2-(1H-Indol-3-yl)-3-pyridin-3-yl-acrylonitrile;(Z)-?-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;(Z)-2-(1H-Indol-3-yl)-3-(pyridin-3-yl)acrylonitrile;MS-23470;MS-23470;MS-23470;MS-23470;MS-23470;MS-23470;CS-6861;CS-6861;CS-6861;CS-6861;CS-6861;CS-6861;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;(2Z)-2-(1H-INDOL-3-YL)-3-(PYRIDIN-3-YL)PROP-2-ENENITRILE;PAssenger PROteins TRAnsport Inhibitor;PAssenger PROteins TRAnsport Inhibitor;PAssenger PROteins TRAnsport Inhibitor;PAssenger PROteins TRAnsport Inhibitor;SCHEMBL2725524;PAssenger PROteins TRAnsport Inhibitor;PAssenger PROteins TRAnsport Inhibitor;SCHEMBL2725524;SCHEMBL2725524;SCHEMBL2725524;SCHEMBL2725524;G12613;SCHEMBL2725524;G12613;G12613;G12613;G12613;GLXC-03480;G12613;GLXC-03480;GLXC-03480;GLXC-03480;GLXC-03480;HY-101298;HY-101298;HY-101298;GLXC-03480;HY-101298;HY-101298;SCHEMBL2725529;SCHEMBL2725529;SCHEMBL2725529;HY-101298;SCHEMBL2725529;SCHEMBL2725529;CHEMBL3753955;SCHEMBL2725529;CHEMBL3753955;CHEMBL3753955;CHEMBL3753955;CHEMBL3753955;DA-66484;CHEMBL3753955;DA-66484;DA-66484;DA-66484;DA-66484;AKOS024458361;DA-66484;AKOS024458361;AKOS024458361;AKOS024458361;AKOS024458361;57046-73-8;AKOS024458361;57046-73-8;57046-73-8;57046-73-8;57046-73-8;MKLP-2 Inhibitor;MKLP-2 Inhibitor;MKLP-2 Inhibitor;57046-73-8;MKLP-2 Inhibitor;MKLP-2 Inhibitor;MKLP-2 Inhibitor
SMILES: N1([H])C([H])=C(/C(/C#N)=C(\[H])/C2=C([H])N=C([H])C([H])=C2[H])C2=C([H])C([H])=C([H])C([H])=C12
Formula: C16H11N3
M.Wt: 245.2786
Purity: 98%
Sotrage: 0°C (short term), -20°C (long term), desiccated
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC31074 Isopropyl myristate Isopropyl myristate is the ester of isopropyl alcohol and myristic acid.
DC75868 AZ14133346 AZ14133346 (compound 36) is a potent and selective inhibitor of EGFR Exon20 insertions, with the IC50 of 85 nM. AZ14133346 plays an important role in cancer research.
DC75865 TI17 ​​TI17​​ represents a novel class of targeted anticancer agents that specifically disrupt DNA damage repair mechanisms in malignant cells.
DC75816 Nisoxetine Nisoxetine acts as a highly selective and potent noradrenaline transporter (NET) antagonist, exhibiting a binding affinity (Kd) of 0.76 nM. In addition to its antidepressant properties, nisoxetine functions as a local anesthetic by inhibiting voltage-gated sodium channels. This dual pharmacological activity makes it a compound of interest for both neurological and pain management research.
DC75641 GENZ-644282 TFA salt Genz-644282, also known as SAR402674, is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity. Topoisomerase I inhibitor Genz-644282 binds to and inhibits the enzyme topoisomerase I, which may result in the inhibition of repair of single-strand DNA breaks, DNA replication, and tumor cell growth in susceptible tumor cell populations.
DC75325 PSMA-617 TFA PSMA-617, also know as vipivotide tetraxetan, is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to fight cancer. PSMA617 possesses a small peptide, which was designed to target prostate-specific membrane antigen (PSMA). PSMA617 demonstrates high radiolytic stability for at least 72 h. PSMA617 has high inhibition potency (equilibrium dissociation constant Ki=2.34±2.94 nM on LNCaP; Ki=0.37±0.21 nM enzymatically determined). 177 Lu-PSMA-617 offers a potential additional life-prolonging treatment option for men with mCRPC.
DC75202 Fosaprepitant free acid Fosaprepitant, also known as MK0517, is an antiemetic drug, administered intravenously. It is a prodrug of aprepitant. Fosaprepitant was developed by Merck & Co. and was approved. It is a prodrug of Aprepitant. It aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. Fosaprepitant is a weak inhibitor of CYP3A4, and aprepitant, the active moiety, is a substrate, inhibitor, and inducer of CYP3A4
DC74748 O4I4 O4I4 (compound 23) is a OCT4-inducing compound with metabolical stability.
DC74684 ZH8667 ZH8667 is a trace amine-associated receptor 1 (TAAR1)–Gs agonist.
DC74646 EB-PSMA-617 EB-PSMA-617 is an Evans blue-modified prostate-specific membrane antigen (PSMA) 617 ligand for making 177Lu-EB-PSMA, which is potential useful for Metastatic Castration-Resistant Prostate Cancer.
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