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preQ1 Dihydrochloride

  Cat. No.:  DC43798   Featured
Chemical Structure
86694-45-3
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More than 5000 active chemicals with high quality for research!
Field of application
preQ1 is a precursor in the biosynthesis of queuosine, a bacterial nucleoside incorporated into tRNA by tRNA transglycosylase. preQ1 binds to an aptamer domain on tRNA that acts as a riboswitch to repress gene expression.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 86694-45-3
Chemical Name: preQ1 Dihydrochloride
Synonyms: 2-Amino-5-aminomethylpyrrolo[2,3-d]pyrimidin-4(3H)-one;B,2HCl-2-Amino-5-aminomethylpyrrolo[2,3-d]pyrimidin-4-one;Pre-queuosine1 dihydrochloride;2-Amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride;7-Aminomethyl-7-deazaguanine dihydrochloride
SMILES: NC1N=C2N=CC(CN)=C2C(=O)N1
Formula: C7H9N5O
M.Wt: 179.17926
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: 1. Okada, N., Noguchi, S., Kasai, H., et al. Novel mechanism of post-transcriptional modification of tRNA. Insertion of bases of Q precursors into tRNA by a specific tRNA transglycosylase reaction. J. Biol. Chem. 254(8), 3067-3073 (1979). 2. Wu, M.-C., L
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