Alternate TextTo enhance service speed and avoid tariff delays, we've opened a US warehouse. All US orders ship directly from our US facility.

CFT7455

  Cat. No.:  DC50245   Featured
Chemical Structure
2504235-67-8
For research use only. We do not sell to patients.
We match the best price and quality on market.
Email:order@dcchemicals.com  sales@dcchemicals.com
Tel:+86 21 58447131
We are official vendor of:
  • 20
  • 19
  • 18
  • 17
  • 16
  • 15
  • 14
  • 12
  • 11
  • 10
  • 9
  • 8
  • 13
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
More than 5000 active chemicals with high quality for research!
Field of application
CFT7455 is an orally bioavailable degrader of the zinc finger transcription factors Ikaros (IKZF1) and Aiolos (IKZF3). It functions as an anticancer agent by binding with high affinity to the cereblon E3 ligase, exhibiting a Kd of 0.9 nM (WO2022032132A1; Compound 1).
Cas No.: 2504235-67-8
Chemical Name: Cemsidomide
Synonyms: 2,​6-​Piperidinedione, 3-​[6-​[[4-​(4-​morpholinylmethyl)​phenyl]​methyl]​-​2-​oxobenz[cd]​indol-​1(2H)​-​yl]​-​, (3S)​-;Cemsidomide
SMILES: O=C1[C@@H](N2C(=O)C3=C4C(C(CC5=CC=C(C=C5)CN5CCOCC5)=CC=C24)=CC=C3)CCC(=O)N1
Formula: C28H27N3O4
M.Wt: 469.53
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC60948 NEK7 degrader (Compound 17) NEK7 degrader-1 is a NEK7 molecular glue degrader with a DC50 of 9  nM. NEK7 degrader-1 dose-dependently inhibits caspase-1 activity and IL-Ιβ release in macrophages in response to NLRP3 inflammasome activation. NEK7 degrader-1 can be used for autoinflammatory and autoimmune disorders like multiple sclerosis, neurodegeneraive diseases like Alzheimer's disease and cardiovascular and melabolic disorders like pericarditis and Type 2 diabetes research.
DC68076 BG-BRD4-P07
DC68075 BRU-SHP2-P06
DC68074 LLY-ESR1-P05
DC68073 AST-AR-P04
DC68072 NOV-EP001
DC68071 JHU-MDM2-P03
DC68070 CAS-FAK-P02
DC68069 MDA-S24-P01
DC68068 TB-008
X